Triorthocresyl phosphate
WebMay 8, 2007 · Working closely with colleagues in other bureaus and laboratories, Dr. Maurice Smith of the U.S. Public Health Service eventually and shortly confirmed that tri-ortho-cresyl phosphate (TOCP) was... WebOrganophosphate insecticides are highly toxic to insects but less so to humans and domestic animals.18 Organophosphates such as triorthocresyl phosphate, mipafox, and trichlorfon compounds can be neurotoxic.
Triorthocresyl phosphate
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WebTriorthocresyl phosphate (TOCP) is an organophosphorus substance that has been responsible for several incidents of mass poisoning. During prohibition, contamination of an alcoholic beverage containing ginger extract with TOCP led to an epidemic that became known as the Ginger-Jake syndrome. WebTOCP (tri-ortho-cresyl phosphate) is known to cause a specific neurodegenerative symptom known as organic phosphate-induced delayed neuropathy (OPIDN) in humans exposed by ingestion. TOCP has been the subject of much scientific research that has focused largely on the mechanism of induction of OPIDN. These studies have been
WebTriorthocresyl phosphate is an organophosphate compound that has been used as an adulterant. In 1930, thousands of Americans developed neurologic deficits after consuming a popular illicit alcoholic beverage (Jamaica ginger extract or “jake”) that had been adulterated with triorthocresyl phosphate [261] . WebTRIORTHOCRESYL PHOSPHATE CAS number: 78-30-8 Synonyms: TOCP; Tri (2-tolyl)ester of phosphoric acid; Tri-o-tolyl phosphate Molecular formula: C 21 H 21 O 4 P Chemical structure: TLV–TWA, 0.02 mg/m Skin logged in as an ACGIH member or have previously purchased the documentation.
WebOct 1, 2007 · Their formation was completely inhibited by the esterase inhibitors, triorthocresyl phosphate (TOCP) and phenylmethylsulfonyl fluoride, but not at all or partially by cytochrome P450 (P450) inhibitors, α-naphthoflavone and proadifen (SKF 525A), respectively. These results demonstrated that both metabolites were produced by … WebJan 29, 2024 · Formula. C₂₁H₂₁O₄P. Synonyms. TCP; TOCP; tri-o-cresyl ester of phosphoric acid; tri-o-cresyl phosphate; tricresyl phosphate. Physical Properties. Physical …
Webtri·orth·o·cres·yl phos·phate (TOCP), ( trī'ōrth-ō-kres'il fos'fāt ), A triaryl phosphate; produces a delayed neurotoxicity. An infamous incident occurred when it appeared in an extract of …
WebTriorthocresyl Phosphate Myopathy JAMA Neurology JAMA Network THE occurrence of widespread epidemics of paralysis caused by adulteration of food with triorthocresyl … map of nantwich cheshireWebto triorthocresyl phosphate were subjected to a pharmacological study for the purpose of correlating their behavior in the animal bodywith certain of their physicochemical properties, such as lipoid solubility andrate ofhydrolysis in titro andin viv,o. The results of this investigation disclosed that by altering the kronos 3 account tradingWebSep 10, 2004 · Tri-ortho-cresyl phosphate (TOCP) is an organophosphorus ester. It is capable of producing organophosphorus ester induced delayed neurotoxicity (OPIDN) in … map of napak districtWebTriorthocresyl Phosphate (Cas. No. 78-30-8); 4,4'-Thiobis (6-t-Butyl-m-Cresol (Cas. No. 96-69-5); 13-Cis Retinoic Acid (Cas. No. 4759-48-2). National Technical Reports Library - NTIS Home Help Details Actions: Download Screening … kronos8.nac.sitel-world.net wfc logonWebTriorthocresyl phosphate: TRI-o-CRESYL PHOSPHATE; NFPA 704. Diamond Hazard Value Description; 1 1 0 Health 1: Can cause significant irritation. Flammability 1: Must be preheated before ignition can occur. Instability 0: Normally stable, even … map of napa california areaWebAs a plasticizer widely used in society, tri-ortho-cresyl phosphate (TOCP) is reported to inhibit spermatogenesis and growth of spermatogonial stem cells. However, its effects on … map of napa auto parts in saskatchewanWebOrganophosphates, such as TRICRESYL PHOSPHATE, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as … map of napa and sonoma ca