WebbCigarette smoke is the major risk factor associated with the development of chronic obstructive pulmonary disease and alters expression of proteolytic enzymes that contribute to disease pathology. Previously, we reported that smoke exposure leads to the induction of matrix metalloproteinase-1 (MMP-1) through the activation of ERK1/2, which … WebbThe small airways are the major site of airflow obstruction in susceptible smokers, leading to accelerated loss of lung function in the early stages of COPD. Representative pictures …
Airway Obstruction: Identifying High-Risk Situations
WebbObstructive lung disease is a category of respiratory disease characterized by airway obstruction. Many obstructive diseases of the lung result from narrowing (obstruction) … WebbBackground: The concept that small conducting airways less than 2 mm in diameter become the major site of airflow obstruction in chronic obstructive pulmonary disease … crypto coin companies
Small airway disease: A new "phenotype" of obstructive airway …
Webb8 apr. 2024 · Background: No short patient-reported outcome (PRO) instruments assess overall health status across different obstructive lung diseases. Thus, the wording of the introduction to the Chronic ... Webb26 juni 2024 · Small airway dysfunction was defined as two of the three indices MMEF, FEF 50%, and FEF 75% with values less than 65%, independent from the FEV 1 /FVC ratio, pre-small airway dysfunction (ie, before bronchodilation) in the presence of a normal FEV 1 /FVC ratio, and post-small airway dysfunction (ie, after bronchodilation) in the presence … WebbBronchodilator responsiveness (BDR) is widely considered to be a key diagnostic criterion for asthma, and is used to differentiate asthma from chronic obstructive pulmonary disease (COPD). Currently, the threshold … durham cc councillors