WebJan 1, 2024 · Bone remodeling, a highly complex process by which old bone is replaced by new bone (bone resorption followed by bone formation), occurs due to the coordinated action of osteoclasts, osteoblasts, osteocytes, and BLCs which together form the temporary anatomical structures called basic multicellular units or bone remodeling units ( Fig. 9.1) ( … WebFeb 9, 2024 · The skeleton adapts to mechanical loading to promote bone formation and remodeling. While most bone cells are involved in mechanosensing, it is well accepted that osteocytes are the principal mechanosensory cells. The osteocyte cell body and processes are surrounded by a fluid-filled space, forming an extensive lacuno-canalicular network. …
[PDF] The Osteocyte: New Insights. Semantic Scholar
WebPreclinical models have also shown that apart from the strain magnitude (De Souza et al., 2005; Robling, Burr, & Turner, 2001), ... Bonewald, 2011). Through apoptosis, osteocytes also elicit the recruitment of osteoclasts toward a remodelling response, and this mechanism also facilitates the repair of microdamage in the bone matrix ... WebInactive osteoblasts are called bone-lining cells; they have the potential of becoming active osteoblasts. The bone cells that are buried in the extracellular bone matrix are the … hellsing scars
Loading and skeletal development and maintenance
WebOsteocytes are embedded within the hard-mineralized component of bone throughout life (exceptions being when released by fracture or during remodeling) (Robling & Bonewald, 2024), providing them... WebOsteocytes are embedded within the hard-mineralized component of bone throughout life (exceptions being when released by fracture or during remodeling) (Robling & Bonewald … WebAlexander G. Robling, Alesha B. Castillo, and Charles H. Turner Annual Review of Biomedical Engineering The Osteocyte: New Insights Alexander G. Robling and Lynda F. Bonewald Annual Review of Physiology Osteoclasts Provide Coupling Signals to Osteoblast Lineage Cells Through Multiple Mechanisms Natalie A. Sims and T. John Martin lake victoria crossgates