Phospho-erk1/2
WebFigure Legend Snippet: Western blot analysis of phosphorylation of IGF-1R and key signaling pathway reporters (AKT and ERK1/2). NTC or EHD1-KO TC71 and A673 cell lines were pre-starved for 24h in low serum/IGF-free medium and left unstimulated (0) or stimulated with IGF-1 (50 ng/ml) for the indicated time points (min, minutes). WebERK1 and ERK2 (also known as MAPK3 and MAPK1) are 44 and 42 kDa Ser/Thr kinases, respectively. They are part of the Ras-Raf-ERK signal transduction cascade often found downstream of growth factor receptor activation. ERK1 and ERK2 were initially isolated and cloned as kinases activated in response to insulin and NGF.
Phospho-erk1/2
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WebNov 23, 2024 · p-ERK 1/2 Antibody (12D4) is a mouse monoclonal IgG 1, cited in 235 publications, provided at 50 µg/0.5 ml raised against synthetic phosphopeptide corresponding to amino acid residues surrounding the T-E-Y motif of ERK1 of human origin WebMEK1/2 catalyze the phosphorylation of ERK1/2 at Tyr204 and Thr202. In response, ERK phosphorylates hundreds of cytoplasmic and nuclear substrates. The wide complexity and diversity of MAPK signaling makes ERK a key regulator and major signaling node in biology. ERK in GPCR signaling
WebThe phospho ERK1/2 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A … WebThe Phospho/Total ERK1/2 Whole Cell Lysate Kit provides assay-specific components for the quantitative determination of phospho-ERK1/2 (Thr202/Tyr204; Thr185/Tyr187) and …
WebThe AlphaLISA SureFire Ultra p-ERK 1/2 (Thr202/Tyr204) assay kit (high volume) is an immunoassay for quantitative detection of phospho-ERK 1/2 in cellular lysates. We are … WebDetects human, mouse, and rat ERK1 and ERK2 dually phosphorylated at T202/Y204 or T185/Y187, respectively. Source Monoclonal Rabbit IgG Clone # 269434 Purification Protein A or G purified from hybridoma culture supernatant Immunogen Phosphopeptide containing ERK1 T202/Y204 site Formulation
WebResults: There are ultrastructural changes in the DM skin. With the continuance of the diabetes course, the thicknesses of the epidermis and dermis decreased, and the expression of phospho-ERK1/2 (P-ERK1/2), EGFR, and ELK-1 was decreased gradually in the back skin of the diabetes rats.
WebNov 21, 2024 · Renal luminal sodium transport is essential for physiological blood pressure control, and abnormalities in this process are strongly implicated in the pathogenesis of essential hypertension. Renal G protein-coupled receptors (GPCRs) are critical for the regulation of the reabsorption of essential nutrients, ions, and water from the glomerular … french today reviewWebAnti-phospho-Erk1/2 (Thr202/Tyr204, Thr185/Tyr187)Antibody, recombinant clone AW39R, rabbit monoclonal Anti-phospho-Erk1/2 (Thr202/Tyr204 Antibody, Thr185/Tyr187), recombinant clone AW39R detects level of phospho-Erk1/2 (Thr202/Tyr204 & has been published & validated for use in Mplex & WB. - Find MSDS or SDS, a COA, data sheets and … fast track email addressWebThe p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli, including mitogens, growth factors, and cytokines (1-3), and … fasttrack employee experienceWebERK1/2 are members of mitogen-activated kinases (MAPKs) of serine/threonine protein kinases. ERK1/2 can be activated by a range of extracellular stimuli, such as mitogen, growth factors, neurotransmitters, chemokines, and cytokines, through receptor tyrosine kinases (RTK), G protein-coupled receptors (GPCRs), or protein kinase C (PKC). fast track emaWebERK1/2 signaling is activated in response to numerous extracellular stimuli including mitogens, growth factors, and cytokines. The primary activators of ERK1/2 are MEK1 and … fast track ems virginiaWebYou need to normalize both with total ERK1/2 (non-phospho) to show the fold increase in phosphorylation and then with house-keeping gene proteins like actin/tubulin etc which serves as your... fast track emirates idWebJun 25, 2015 · National Center for Biotechnology Information fast track ems llc