WebDec 23, 2024 · Family with sequence similarity 72 A (FAM72A) is a pivotal mitosis-promoting factor that is highly expressed in various types of cancer. FAM72A interacts … WebJan 1, 2024 · Download Citation On Jan 1, 2024, Yibin Zeng and others published FAM72A promotes glioma progression by regulating mitophagy through the Pink1/Parkin signaling pathway Find, read and cite all ...
FAM72A family with sequence similarity 72 member A [ (human)]
WebApr 1, 2007 · UNG2 and SMUG1 are both important for prevention of mutations caused by cytosine deamination, and their functions are non-redundant. In addition, SMUG1 has a major role in removal of hydroxymethyl uracil from oxidized thymines. Furthermore, UNG-proteins and SMUG1 may have important functions in removal of oxidized cytosines, e.g. … Web"FAM72A Antagonizes UNG2 to Promote Mutagenic Repair During Antibody Maturation" 11:55 am - 12:00 pm: Discussion. 12:00 pm - 12:20 pm: Sergei Mirkin (Tufts University, United States) "Genomic Weak Links: Mechanisms of Genome Instability Caused by Structure-Prone DNA Repeats" 12:20 pm - 12:30 pm: Discussion. 12:30 pm - 1:30 pm: pymalloc机制
FAM72A antagonizes UNG2 to promote mutagenic repair during …
WebAug 1, 2024 · Yet, the mechanisms by which FAM72A regulates UNG2 degradation is an open question. It has been suggested that different genetic loci might exhibit different … WebFeb 1, 2024 · FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation Nature 2024. 600(7888):324-328. (PMID: 34819670) Abstract Full Text Link. Sherker A, Chaudhary N, Adam S, Noordermeer SM, Fradet-Turcotte, Durocher D. Two redundant ubiquitin-dependent pathways of BRCA1 localization to DNA damage sites WebIn the present study, we determined a specific FAM72A-UNG2 heterodimer protein interaction using molecular docking and dynamics. In addition, through in silico screening, we identified withaferin B as a molecule that can specifically prevent the FAM72A-UNG2 interaction by blocking its cell signaling pathways. Our results provide an excellent ... pym kitchen paris